Inhibition of impulsive action by projection-defined prefrontal pyramidal neurons
Inhibition of impulsive action by projection-defined prefrontal pyramidal neurons
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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The prefrontal cortex (PFC) plays a critical role in curbing impulsive behavior, but the underlying circuit mechanism remains incompletely understood. Here we show that a subset of dorsomedial PFC (dmPFC) layer 5 pyramidal neurons, which project to the subthalamic nucleus (STN) of the basal ganglia, play a key role in inhibiting impulsive responses...
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Full title
Inhibition of impulsive action by projection-defined prefrontal pyramidal neurons
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7382266
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7382266
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2000523117