Tumor cell lysate-loaded immunostimulatory spherical nucleic acids as therapeutics for triple-negati...
Tumor cell lysate-loaded immunostimulatory spherical nucleic acids as therapeutics for triple-negative breast cancer
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Publisher
United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Scope and Contents
Contents
Highly heterogenous cancers, such as triple-negative breast cancer (TNBC), remain challenging immunotherapeutic targets. Herein, we describe the synthesis and evaluation of immunotherapeutic liposomal spherical nucleic acids (SNAs) for TNBC therapy. The SNAs comprise immunostimulatory oligonucleotides (CpG-1826) as adjuvants and encapsulate lysates...
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Full title
Tumor cell lysate-loaded immunostimulatory spherical nucleic acids as therapeutics for triple-negative breast cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7395518
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7395518
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2005794117