Adaptive response to inflammation contributes to sustained myelopoiesis and confers a competitive ad...
Adaptive response to inflammation contributes to sustained myelopoiesis and confers a competitive advantage in myelodysplastic syndrome HSCs
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
Despite evidence of chronic inflammation in myelodysplastic syndrome (MDS) and cell-intrinsic dysregulation of Toll-like receptor (TLR) signaling in MDS hematopoietic stem and progenitor cells (HSPCs), the mechanisms responsible for the competitive advantage of MDS HSPCs in an inflammatory milieu over normal HSPCs remain poorly defined. Here, we fo...
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Full title
Adaptive response to inflammation contributes to sustained myelopoiesis and confers a competitive advantage in myelodysplastic syndrome HSCs
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7402480
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7402480
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-020-0663-z
