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Protein Degradation and the Pathologic Basis of Phenylketonuria and Hereditary Tyrosinemia

Protein Degradation and the Pathologic Basis of Phenylketonuria and Hereditary Tyrosinemia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7404301

Protein Degradation and the Pathologic Basis of Phenylketonuria and Hereditary Tyrosinemia

About this item

Full title

Protein Degradation and the Pathologic Basis of Phenylketonuria and Hereditary Tyrosinemia

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2020-07, Vol.21 (14), p.4996

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

A delicate intracellular balance among protein synthesis, folding, and degradation is essential to maintaining protein homeostasis or proteostasis, and it is challenged by genetic and environmental factors. Molecular chaperones and the ubiquitin proteasome system (UPS) play a vital role in proteostasis for normal cellular function. As part of prote...

Alternative Titles

Full title

Protein Degradation and the Pathologic Basis of Phenylketonuria and Hereditary Tyrosinemia

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7404301

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7404301

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms21144996

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