Elevated circulating amyloid concentrations in obesity and diabetes promote vascular dysfunction
Elevated circulating amyloid concentrations in obesity and diabetes promote vascular dysfunction
About this item
Full title
Author / Creator
Meakin, Paul J , Coull, Bethany M , Tuharska, Zofia , McCaffery, Christopher , Akoumianakis, Ioannis , Antoniades, Charalambos , Brown, Jane , Griffin, Kathryn J , Platt, Fiona , Ozber, Claire H , Yuldasheva, Nadira Y , Makava, Natallia , Skromna, Anna , Prescott, Alan , McNeilly, Alison D , Siddiqui, Moneeza , Palmer, Colin Na , Khan, Faisel and Ashford, Michael Lj
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Diabetes, obesity, and Alzheimer's disease (AD) are associated with vascular complications and impaired nitric oxide (NO) production. Furthermore, increased β-site amyloid precursor protein-cleaving (APP-cleaving) enzyme 1 (BACE1), APP, and β-amyloid (Aβ) are linked with vascular disease development and increased BACE1 and Aβ accompany hyperglycemi...
Alternative Titles
Full title
Elevated circulating amyloid concentrations in obesity and diabetes promote vascular dysfunction
Authors, Artists and Contributors
Author / Creator
Coull, Bethany M
Tuharska, Zofia
McCaffery, Christopher
Akoumianakis, Ioannis
Antoniades, Charalambos
Brown, Jane
Griffin, Kathryn J
Platt, Fiona
Ozber, Claire H
Yuldasheva, Nadira Y
Makava, Natallia
Skromna, Anna
Prescott, Alan
McNeilly, Alison D
Siddiqui, Moneeza
Palmer, Colin Na
Khan, Faisel
Ashford, Michael Lj
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7410081
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7410081
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI122237
