Gut Hormone GIP Induces Inflammation and Insulin Resistance in the Hypothalamus
Gut Hormone GIP Induces Inflammation and Insulin Resistance in the Hypothalamus
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Publisher
US: Oxford University Press
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Language
English
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Publisher
US: Oxford University Press
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Abstract
The hypothalamus plays a critical role in controlling energy balance. High-fat diet (HFD) feeding increases the gene expression of proinflammatory mediators and decreases insulin actions in the hypothalamus. Here, we show that a gut-derived hormone, glucose-dependent insulinotropic polypeptide (GIP), whose levels are elevated during die...
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Full title
Gut Hormone GIP Induces Inflammation and Insulin Resistance in the Hypothalamus
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7410368
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7410368
Other Identifiers
ISSN
0013-7227
E-ISSN
1945-7170
DOI
10.1210/endocr/bqaa102
