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The GATA3 X308_Splice breast cancer mutation is a hormone context-dependent oncogenic driver

The GATA3 X308_Splice breast cancer mutation is a hormone context-dependent oncogenic driver

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7410826

The GATA3 X308_Splice breast cancer mutation is a hormone context-dependent oncogenic driver

About this item

Full title

The GATA3 X308_Splice breast cancer mutation is a hormone context-dependent oncogenic driver

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2020-08, Vol.39 (32), p.5455-5467

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

As the catalog of oncogenic driver mutations is expanding, it becomes clear that alterations in a given gene might have different functions and should not be lumped into one class. The transcription factor
GATA3
is a paradigm of this. We investigated the functions of the most common
GATA3
mutation (X308_Splice) and five additional mutat...

Alternative Titles

Full title

The GATA3 X308_Splice breast cancer mutation is a hormone context-dependent oncogenic driver

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7410826

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7410826

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/s41388-020-1376-3

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