Effect of allosteric inhibition of non-muscle myosin 2 on its intracellular diffusion
Effect of allosteric inhibition of non-muscle myosin 2 on its intracellular diffusion
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Subcellular dynamics of non-muscle myosin 2 (NM2) is crucial for a broad-array of cellular functions. To unveil mechanisms of NM2 pharmacological control, we determined how the dynamics of NM2 diffusion is affected by NM2′s allosteric inhibitors, i.e. blebbistatin derivatives, as compared to Y-27632 inhibiting ROCK, NM2′s upstream regulator. We fou...
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Full title
Effect of allosteric inhibition of non-muscle myosin 2 on its intracellular diffusion
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7415145
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7415145
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-69853-8
