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The role of IgG Fc receptors in antibody-dependent enhancement

The role of IgG Fc receptors in antibody-dependent enhancement

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7418887

The role of IgG Fc receptors in antibody-dependent enhancement

About this item

Full title

The role of IgG Fc receptors in antibody-dependent enhancement

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Immunology, 2020-10, Vol.20 (10), p.633-643

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Antibody-dependent enhancement (ADE) is a mechanism by which the pathogenesis of certain viral infections is enhanced in the presence of sub-neutralizing or cross-reactive non-neutralizing antiviral antibodies. In vitro modelling of ADE has attributed enhanced pathogenesis to Fcγ receptor (FcγR)-mediated viral entry, rather than canonical viral rec...

Alternative Titles

Full title

The role of IgG Fc receptors in antibody-dependent enhancement

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7418887

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7418887

Other Identifiers

ISSN

1474-1733

E-ISSN

1474-1741

DOI

10.1038/s41577-020-00410-0

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