Costello syndrome model mice with a HrasG12S/+ mutation are susceptible to develop house dust mite-i...
Costello syndrome model mice with a HrasG12S/+ mutation are susceptible to develop house dust mite-induced atopic dermatitis
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Costello syndrome is an autosomal dominant disorder that is caused by germline
HRAS
mutations. Patients with Costello syndrome present craniofacial abnormalities, cardiac defects, and cancer predisposition, as well as skin abnormalities, including papillomas, keratosis pilaris, and eczematous dermatitis. However, the mechanisms underlying the...
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Full title
Costello syndrome model mice with a HrasG12S/+ mutation are susceptible to develop house dust mite-induced atopic dermatitis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7426869
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7426869
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E-ISSN
2041-4889
DOI
10.1038/s41419-020-02845-8
