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The role of a monoclonal antibody 11C8B1 as a diagnostic marker of IDH2-mutated sinonasal undifferen...

The role of a monoclonal antibody 11C8B1 as a diagnostic marker of IDH2-mutated sinonasal undifferen...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7429919

The role of a monoclonal antibody 11C8B1 as a diagnostic marker of IDH2-mutated sinonasal undifferentiated carcinoma

About this item

Full title

The role of a monoclonal antibody 11C8B1 as a diagnostic marker of IDH2-mutated sinonasal undifferentiated carcinoma

Publisher

New York: Nature Publishing Group US

Journal title

Modern pathology, 2019-02, Vol.32 (2), p.205-215

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

IDH2
R172 mutations occur in >80% sinonasal undifferentiated carcinomas (“SNUC”) and ~80% of these are R172S and R172T variants. We examined the utility of the monoclonal antibody 11C8B1 to
IDH2
R172S in
IDH2
R172-mutated tumors to establish an immunohistochemistry protocol as a surrogate method for
IDH2
R172S mutation detectio...

Alternative Titles

Full title

The role of a monoclonal antibody 11C8B1 as a diagnostic marker of IDH2-mutated sinonasal undifferentiated carcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7429919

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7429919

Other Identifiers

ISSN

0893-3952

E-ISSN

1530-0285

DOI

10.1038/s41379-018-0126-3

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