Aging aggravated liver ischemia and reperfusion injury by promoting STING‐mediated NLRP3 activation...
Aging aggravated liver ischemia and reperfusion injury by promoting STING‐mediated NLRP3 activation in macrophages
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Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
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Publisher
England: John Wiley & Sons, Inc
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Scope and Contents
Contents
Although aggravated liver injury has been reported in aged livers post‐ischemia and reperfusion (IR), the underlying mechanism of innate immune activation of aged macrophages is not well understood. Here, we investigated whether and how Stimulator of interferon genes (STING) signaling regulated macrophage proinflammatory activation and liver IR inj...
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Full title
Aging aggravated liver ischemia and reperfusion injury by promoting STING‐mediated NLRP3 activation in macrophages
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7431827
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7431827
Other Identifiers
ISSN
1474-9718
E-ISSN
1474-9726
DOI
10.1111/acel.13186