High-Throughput Liquid Chromatography–Tandem Mass Spectrometry Quantification of Glycosaminoglycans...
High-Throughput Liquid Chromatography–Tandem Mass Spectrometry Quantification of Glycosaminoglycans as Biomarkers of Mucopolysaccharidosis II
About this item
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Author / Creator
Wang, Junhua , Bhalla, Akhil , Ullman, Julie C. , Fang, Meng , Ravi, Ritesh , Arguello, Annie , Thomsen, Elliot , Tsogtbaatar, Buyankhishig , Guo, Jing L. , Skuja, Lukas L. , Dugas, Jason C. , Davis, Sonnet S. , Poda, Suresh B. , Gunasekaran, Kannan , Costanzo, Simona , Sweeney, Zachary K. , Henry, Anastasia G. , Harris, Jeffrey M. , Henne, Kirk R. and Astarita, Giuseppe
Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publication information
Publisher
Switzerland: MDPI AG
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More information
Scope and Contents
Contents
We recently developed a blood–brain barrier (BBB)-penetrating enzyme transport vehicle (ETV) fused to the lysosomal enzyme iduronate 2-sulfatase (ETV:IDS) and demonstrated its ability to reduce glycosaminoglycan (GAG) accumulation in the brains of a mouse model of mucopolysaccharidosis (MPS) II. To accurately quantify GAGs, we developed a plate-bas...
Alternative Titles
Full title
High-Throughput Liquid Chromatography–Tandem Mass Spectrometry Quantification of Glycosaminoglycans as Biomarkers of Mucopolysaccharidosis II
Authors, Artists and Contributors
Author / Creator
Bhalla, Akhil
Ullman, Julie C.
Fang, Meng
Ravi, Ritesh
Arguello, Annie
Thomsen, Elliot
Tsogtbaatar, Buyankhishig
Guo, Jing L.
Skuja, Lukas L.
Dugas, Jason C.
Davis, Sonnet S.
Poda, Suresh B.
Gunasekaran, Kannan
Costanzo, Simona
Sweeney, Zachary K.
Henry, Anastasia G.
Harris, Jeffrey M.
Henne, Kirk R.
Astarita, Giuseppe
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7432392
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7432392
Other Identifiers
ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms21155449
