The human papillomavirus E6 protein targets apoptosis-inducing factor (AIF) for degradation
The human papillomavirus E6 protein targets apoptosis-inducing factor (AIF) for degradation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Oncoprotein E6 of high-risk human papillomavirus (HPV) plays a critical role in inducing cell immortalization and malignancy. E6 downregulates caspase-dependent pathway through the degradation of p53. However, the effect of HPV E6 on other pathways is still under investigation. In the present study, we found that HPV E6 directly binds to all three...
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The human papillomavirus E6 protein targets apoptosis-inducing factor (AIF) for degradation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7450093
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7450093
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-71134-3
