Importance of structure-based studies for the design of a novel HIV-1 inhibitor peptide
Importance of structure-based studies for the design of a novel HIV-1 inhibitor peptide
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Based on the structure of an HIV-1 entry inhibitor peptide two stapled- and a retro-enantio peptides have been designed to provide novel prevention interventions against HIV transmission. The three peptides show greater inhibitory potencies in cellular and mucosal tissue pre-clinical models than the parent sequence and the retro-enantio shows a str...
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Full title
Importance of structure-based studies for the design of a novel HIV-1 inhibitor peptide
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7468280
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7468280
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-71404-0
