cDC1 prime and are licensed by CD4+ T cells to induce anti-tumour immunity
cDC1 prime and are licensed by CD4+ T cells to induce anti-tumour immunity
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Author / Creator
Ferris, Stephen T. , Durai, Vivek , Wu, Renee , Theisen, Derek J. , Ward, Jeffrey P. , Bern, Michael D. , Davidson, Jesse T. , Bagadia, Prachi , Liu, Tiantian , Briseño, Carlos G. , Li, Lijin , Gillanders, William E. , Wu, Gregory F. , Yokoyama, Wayne M. , Murphy, Theresa L. , Schreiber, Robert D. and Murphy, Kenneth M.
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Conventional type 1 dendritic cells (cDC1)
1
are thought to perform antigen cross-presentation, which is required to prime CD8
+
T cells
2
,
3
, whereas cDC2 are specialized for priming CD4
+
T cells
4
,
5
. CD4
+
T cells are also considered to help CD8
+
T cell responses through a variety of me...
Alternative Titles
Full title
cDC1 prime and are licensed by CD4+ T cells to induce anti-tumour immunity
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7469755
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7469755
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-020-2611-3