Crossroads of telomere biology and anticancer drug discovery
Crossroads of telomere biology and anticancer drug discovery
About this item
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Author / Creator
Publisher
Tokyo: John Wiley & Sons, Inc
Journal title
Language
English
Formats
Publication information
Publisher
Tokyo: John Wiley & Sons, Inc
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Scope and Contents
Contents
The telomere is the specialized nucleoprotein complex at the end of the chromosome. Its highly conserved 5′‐TTAGGG‐3′ repeats and shelterin protein complexes form a protective loop structure to maintain the integrity and stability of linear chromosomes. Although human somatic cells gradually shorten telomeres to undergo senescence or crisis, cancer...
Alternative Titles
Full title
Crossroads of telomere biology and anticancer drug discovery
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7469838
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7469838
Other Identifiers
ISSN
1347-9032
E-ISSN
1349-7006
DOI
10.1111/cas.14540