Log in to save to my catalogue

Crossroads of telomere biology and anticancer drug discovery

Crossroads of telomere biology and anticancer drug discovery

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7469838

Crossroads of telomere biology and anticancer drug discovery

About this item

Full title

Crossroads of telomere biology and anticancer drug discovery

Author / Creator

Publisher

Tokyo: John Wiley & Sons, Inc

Journal title

Cancer science, 2020-09, Vol.111 (9), p.3089-3099

Language

English

Formats

Publication information

Publisher

Tokyo: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

The telomere is the specialized nucleoprotein complex at the end of the chromosome. Its highly conserved 5′‐TTAGGG‐3′ repeats and shelterin protein complexes form a protective loop structure to maintain the integrity and stability of linear chromosomes. Although human somatic cells gradually shorten telomeres to undergo senescence or crisis, cancer...

Alternative Titles

Full title

Crossroads of telomere biology and anticancer drug discovery

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7469838

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7469838

Other Identifiers

ISSN

1347-9032

E-ISSN

1349-7006

DOI

10.1111/cas.14540

How to access this item