MMR Deficiency is Homogeneous in Pancreatic Carcinoma and Associated with High Density of Cd8-Positi...
MMR Deficiency is Homogeneous in Pancreatic Carcinoma and Associated with High Density of Cd8-Positive Lymphocytes
About this item
Full title
Author / Creator
Fraune, Christoph , Burandt, Eike , Simon, Ronald , Hube-Magg, Claudia , Makrypidi-Fraune, Georgia , Kluth, Martina , Büscheck, Franziska , Höflmayer, Doris , Blessin, Niclas Ch , Mandelkow, Tim , Li, Wenchao , Perez, Daniel , Izbicki, Jakob R. , Wilczak, Waldemar , Sauter, Guido , Schrader, Jörg , Neipp, Michael , Mofid, Hamid , Daniels, Thies , Isbert, Christoph , Clauditz, Till S. and Steurer, Stefan
Publisher
Cham: Springer International Publishing
Journal title
Language
English
Formats
Publication information
Publisher
Cham: Springer International Publishing
Subjects
More information
Scope and Contents
Contents
Background
Microsatellite instability (MSI) has emerged as a predictive biomarker for immune checkpoint inhibitor therapy. Cancer heterogeneity represents a potential obstacle for the analysis of predicitive biomarkers. MSI has been reported in pancreatic cancer, but data on the possible extent of intratumoral heterogeneity are lacking.
Metho...
Alternative Titles
Full title
MMR Deficiency is Homogeneous in Pancreatic Carcinoma and Associated with High Density of Cd8-Positive Lymphocytes
Authors, Artists and Contributors
Author / Creator
Burandt, Eike
Simon, Ronald
Hube-Magg, Claudia
Makrypidi-Fraune, Georgia
Kluth, Martina
Büscheck, Franziska
Höflmayer, Doris
Blessin, Niclas Ch
Mandelkow, Tim
Li, Wenchao
Perez, Daniel
Izbicki, Jakob R.
Wilczak, Waldemar
Sauter, Guido
Schrader, Jörg
Neipp, Michael
Mofid, Hamid
Daniels, Thies
Isbert, Christoph
Clauditz, Till S.
Steurer, Stefan
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7471097
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7471097
Other Identifiers
ISSN
1068-9265
E-ISSN
1534-4681
DOI
10.1245/s10434-020-08209-y
