KAT5 acetylates cGAS to promote innate immune response to DNA virus
KAT5 acetylates cGAS to promote innate immune response to DNA virus
About this item
Full title
Author / Creator
Song, Ze-Min , Lin, Heng , Yi, Xue-Mei , Guo, Wei , Hu, Ming-Ming and Shu, Hong-Bing
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
The DNA sensor cGMP-AMP synthase (cGAS) senses cytosolic microbial or self DNA to initiate a MITA/STING-dependent innate immune response. cGAS is regulated by various posttranslational modifications at its C-terminal catalytic domain. Whether and how its N-terminal unstructured domain is regulated by posttranslational modifications remain unknown....
Alternative Titles
Full title
KAT5 acetylates cGAS to promote innate immune response to DNA virus
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7474609
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7474609
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1922330117
