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Decoding three distinct states of the Syntaxin17 SNARE motif in mediating autophagosome–lysosome fus...

Decoding three distinct states of the Syntaxin17 SNARE motif in mediating autophagosome–lysosome fus...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7474698

Decoding three distinct states of the Syntaxin17 SNARE motif in mediating autophagosome–lysosome fusion

About this item

Full title

Decoding three distinct states of the Syntaxin17 SNARE motif in mediating autophagosome–lysosome fusion

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2020-09, Vol.117 (35), p.21391-21402

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Syntaxin17, a key autophagosomal N-ethylmaleimide–sensitive factor attachment protein receptor (SNARE) protein, can associate with ATG8 family proteins SNAP29 and VAMP8 to facilitate the membrane fusion process between the double-membraned autophagosome and single-membraned lysosome in mammalian macroautophagy. However, the inherent properties of S...

Alternative Titles

Full title

Decoding three distinct states of the Syntaxin17 SNARE motif in mediating autophagosome–lysosome fusion

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7474698

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7474698

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.2006997117

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