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Microglia phagocytose myelin sheaths to modify developmental myelination

Microglia phagocytose myelin sheaths to modify developmental myelination

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7483351

Microglia phagocytose myelin sheaths to modify developmental myelination

About this item

Full title

Microglia phagocytose myelin sheaths to modify developmental myelination

Publisher

New York: Nature Publishing Group US

Journal title

Nature neuroscience, 2020-09, Vol.23 (9), p.1055-1066

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

During development, oligodendrocytes contact and wrap neuronal axons with myelin. Similarly to neurons and synapses, excess myelin sheaths are produced and selectively eliminated, but how elimination occurs is unknown. Microglia, the resident immune cells of the central nervous system, engulf surplus neurons and synapses. To determine whether micro...

Alternative Titles

Full title

Microglia phagocytose myelin sheaths to modify developmental myelination

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7483351

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7483351

Other Identifiers

ISSN

1097-6256

E-ISSN

1546-1726

DOI

10.1038/s41593-020-0654-2

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