Effects of hyperinsulinemia on acquired resistance to epidermal growth factor receptor‑tyrosine kina...
Effects of hyperinsulinemia on acquired resistance to epidermal growth factor receptor‑tyrosine kinase inhibitor via the PI3K/AKT pathway in non‑small cell lung cancer cells in vitro
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Athens: Spandidos Publications
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Language
English
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Athens: Spandidos Publications
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Contents
Patients with lung cancer harboring activating epidermal growth factor (EGFR) mutations and pre-existing diabetes have been demonstrated to exhibit poor responses to first-line EGFR-tyrosine kinase inhibitor (TKI) therapy. Strategies for the management of acquired resistance to EGFR-TKIs in patients with advanced non-small cell lung cancer (NSCLC)...
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Full title
Effects of hyperinsulinemia on acquired resistance to epidermal growth factor receptor‑tyrosine kinase inhibitor via the PI3K/AKT pathway in non‑small cell lung cancer cells in vitro
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7491043
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7491043
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ISSN
1792-1074
E-ISSN
1792-1082
DOI
10.3892/ol.2020.12069