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Staufen 1 amplifies proapoptotic activation of the unfolded protein response

Staufen 1 amplifies proapoptotic activation of the unfolded protein response

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7492261

Staufen 1 amplifies proapoptotic activation of the unfolded protein response

About this item

Full title

Staufen 1 amplifies proapoptotic activation of the unfolded protein response

Publisher

London: Nature Publishing Group UK

Journal title

Cell death and differentiation, 2020-10, Vol.27 (10), p.2942-2951

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Staufen-1 (STAU1) is an RNA-binding protein that becomes highly overabundant in numerous neurodegenerative disease models, including those carrying mutations in presenilin1 (PSEN1), microtubule-associated protein tau (
MAPT
), huntingtin (
HTT
), TAR DNA-binding protein-43 gene (
TARDBP
), or C9orf72. We previously reported that e...

Alternative Titles

Full title

Staufen 1 amplifies proapoptotic activation of the unfolded protein response

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7492261

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7492261

Other Identifiers

ISSN

1350-9047

E-ISSN

1476-5403

DOI

10.1038/s41418-020-0553-9

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