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Chemical strategies to overcome resistance against targeted anticancer therapeutics

Chemical strategies to overcome resistance against targeted anticancer therapeutics

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7510053

Chemical strategies to overcome resistance against targeted anticancer therapeutics

About this item

Full title

Chemical strategies to overcome resistance against targeted anticancer therapeutics

Author / Creator

Publisher

New York: Nature Publishing Group US

Journal title

Nature chemical biology, 2020-08, Vol.16 (8), p.817-825

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Emergence of resistance is a major factor limiting the efficacy of molecularly targeted anticancer drugs. Understanding the specific mutations, or other genetic or cellular changes, that confer drug resistance can help in the development of therapeutic strategies with improved efficacies. Here, we outline recent progress in understanding chemotype-...

Alternative Titles

Full title

Chemical strategies to overcome resistance against targeted anticancer therapeutics

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7510053

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7510053

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/s41589-020-0596-8

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