TLR9 deficiency alleviates doxorubicin‐induced cardiotoxicity via the regulation of autophagy
TLR9 deficiency alleviates doxorubicin‐induced cardiotoxicity via the regulation of autophagy
About this item
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Author / Creator
Guo, Zhen , Tang, Nan , Liu, Fang‐Yuan , Yang, Zheng , Ma, Shu‐Qing , An, Peng , Wu, Hai‐Ming , Fan, Di and Tang, Qi‐Zhu
Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
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Publication information
Publisher
England: John Wiley & Sons, Inc
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Scope and Contents
Contents
Doxorubicin is a commonly used anthracycline chemotherapeutic drug. Its application for treatment has been impeded by its cardiotoxicity as it is detrimental and fatal. DNA damage, cardiac inflammation, oxidative stress and cell death are the critical links in DOX‐induced myocardial injury. Previous studies found that TLR9‐related signalling pathwa...
Alternative Titles
Full title
TLR9 deficiency alleviates doxorubicin‐induced cardiotoxicity via the regulation of autophagy
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7521247
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7521247
Other Identifiers
ISSN
1582-1838
E-ISSN
1582-4934
DOI
10.1111/jcmm.15719
