Highly infectious prions are not directly neurotoxic
Highly infectious prions are not directly neurotoxic
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Prions are infectious agents which cause rapidly lethal neurodegenerative diseases in humans and animals following long, clinically silent incubation periods. They are composed of multichain assemblies of misfolded cellular prion protein. While it has long been assumed that prions are themselves neurotoxic, recent development of methods to obtain e...
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Full title
Highly infectious prions are not directly neurotoxic
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7525444
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7525444
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2007406117