The contribution of rare variation to prostate cancer heritability
The contribution of rare variation to prostate cancer heritability
About this item
Full title
Author / Creator
Mancuso, Nicholas , Rohland, Nadin , Rand, Kristin A , Tandon, Arti , Allen, Alexander , Quinque, Dominique , Mallick, Swapan , Li, Heng , Stram, Alex , Sheng, Xin , Kote-Jarai, Zsofia , Easton, Douglas F , Eeles, Rosalind A , Le Marchand, Loic , Lubwama, Alex , Stram, Daniel , Watya, Stephen , Conti, David V , Henderson, Brian , Haiman, Christopher A , Pasaniuc, Bogdan , Reich, David , the PRACTICAL consortium and PRACTICAL consortium
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Christopher Haiman, Bogdan Pasaniuc, David Reich and colleagues report a major role for low-frequency variation in the risk for prostate cancer. They show that alleles with >1% minor allele frequency contribute an order of magnitude more to risk for prostate cancer than these alleles do to overall genetic variation.
We report targeted sequencing...
Alternative Titles
Full title
The contribution of rare variation to prostate cancer heritability
Authors, Artists and Contributors
Author / Creator
Rohland, Nadin
Rand, Kristin A
Tandon, Arti
Allen, Alexander
Quinque, Dominique
Mallick, Swapan
Li, Heng
Stram, Alex
Sheng, Xin
Kote-Jarai, Zsofia
Easton, Douglas F
Eeles, Rosalind A
Le Marchand, Loic
Lubwama, Alex
Stram, Daniel
Watya, Stephen
Conti, David V
Henderson, Brian
Haiman, Christopher A
Pasaniuc, Bogdan
Reich, David
the PRACTICAL consortium
PRACTICAL consortium
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7534691
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7534691
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.3446
