Endogenous YAP1 activation drives immediate onset of cervical carcinoma in situ in mice
Endogenous YAP1 activation drives immediate onset of cervical carcinoma in situ in mice
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Author / Creator
Nishio, Miki , To, Yoko , Maehama, Tomohiko , Aono, Yukari , Otani, Junji , Hikasa, Hiroki , Kitagawa, Akihiro , Mimori, Koshi , Sasaki, Takehiko , Nishina, Hiroshi , Toyokuni, Shinya , Lydon, John P. , Nakao, Kazuwa , Wah Mak, Tak , Kiyono, Tohru , Katabuchi, Hidetaka , Tashiro, Hironori and Suzuki, Akira
Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
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Publication information
Publisher
England: John Wiley & Sons, Inc
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Scope and Contents
Contents
Cervical cancer (CC) is usually initiated by infection with high‐risk types of human papillomavirus (HPV). The HPV E6 and E7 proteins target p53 and RB, respectively, but other cellular targets likely exist. We generated uterus‐specific MOB1A/B double KO (uMob1DKO) mice, which immediately developed cervical squamous cell carcinoma in situ. Mutant c...
Alternative Titles
Full title
Endogenous YAP1 activation drives immediate onset of cervical carcinoma in situ in mice
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7541006
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7541006
Other Identifiers
ISSN
1347-9032
E-ISSN
1349-7006
DOI
10.1111/cas.14581
