In vivo detection of antigen-specific CD8+ T cells by immuno-positron emission tomography
In vivo detection of antigen-specific CD8+ T cells by immuno-positron emission tomography
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Author / Creator
Woodham, Andrew W. , Zeigler, Stad H. , Zeyang, Ella L. , Kolifrath, Stephen C. , Cheloha, Ross W. , Rashidian, Mohammad , Chaparro, Rodolfo J. , Seidel, Ronald D. , Garforth, Scott J. , Dearling, Jason L. , Mesyngier, Maia , Duddempudi, Phaneendra K. , Packard, Alan B. , Almo, Steven C. and Ploegh, Hidde L.
Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
The immune system’s ability to recognize peptides on major histocompatibility molecules contributes to the eradication of cancers and pathogens. Tracking these responses in vivo could help evaluate the efficacy of immune interventions and improve mechanistic understanding of immune responses. For this purpose, we employ synTacs, which are dimeric m...
Alternative Titles
Full title
In vivo detection of antigen-specific CD8+ T cells by immuno-positron emission tomography
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7541633
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7541633
Other Identifiers
ISSN
1548-7091,1548-7105
E-ISSN
1548-7105
DOI
10.1038/s41592-020-0934-5
