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NADPH homeostasis in cancer: functions, mechanisms and therapeutic implications

NADPH homeostasis in cancer: functions, mechanisms and therapeutic implications

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7542157

NADPH homeostasis in cancer: functions, mechanisms and therapeutic implications

About this item

Full title

NADPH homeostasis in cancer: functions, mechanisms and therapeutic implications

Publisher

London: Nature Publishing Group UK

Journal title

Signal transduction and targeted therapy, 2020-10, Vol.5 (1), p.231-231, Article 231

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Nicotinamide adenine dinucleotide phosphate (NADPH) is an essential electron donor in all organisms, and provides the reducing power for anabolic reactions and redox balance. NADPH homeostasis is regulated by varied signaling pathways and several metabolic enzymes that undergo adaptive alteration in cancer cells. The metabolic reprogramming of NADP...

Alternative Titles

Full title

NADPH homeostasis in cancer: functions, mechanisms and therapeutic implications

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7542157

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7542157

Other Identifiers

ISSN

2059-3635,2095-9907

E-ISSN

2059-3635

DOI

10.1038/s41392-020-00326-0

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