Projection-specific deficits in synaptic transmission in adult Sapap3-knockout mice
Projection-specific deficits in synaptic transmission in adult Sapap3-knockout mice
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England: Nature Publishing Group
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English
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England: Nature Publishing Group
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Obsessive-compulsive disorder (OCD) is a circuit disorder involving corticostriatal projections, which play a role in motor control. The Sapap3-knockout (KO) mouse is a mouse model to study OCD and recapitulates OCD-like compulsion through excessive grooming behavior, with skin lesions appearing at advanced age. Deficits in corticostriatal control...
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Full title
Projection-specific deficits in synaptic transmission in adult Sapap3-knockout mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7547074
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7547074
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ISSN
0893-133X
E-ISSN
1740-634X
DOI
10.1038/s41386-020-0747-3
