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Combined Atoh1 and Neurod1 Deletion Reveals Autonomous Growth of Auditory Nerve Fibers

Combined Atoh1 and Neurod1 Deletion Reveals Autonomous Growth of Auditory Nerve Fibers

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7547283

Combined Atoh1 and Neurod1 Deletion Reveals Autonomous Growth of Auditory Nerve Fibers

About this item

Full title

Combined Atoh1 and Neurod1 Deletion Reveals Autonomous Growth of Auditory Nerve Fibers

Publisher

New York: Springer US

Journal title

Molecular neurobiology, 2020-12, Vol.57 (12), p.5307-5323

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Ear development requires the transcription factors ATOH1 for hair cell differentiation and NEUROD1 for sensory neuron development. In addition, NEUROD1 negatively regulates
Atoh1
gene expression. As we previously showed that deletion of the
Neurod1
gene in the cochlea results in axon guidance defects and excessive peripheral innervation...

Alternative Titles

Full title

Combined Atoh1 and Neurod1 Deletion Reveals Autonomous Growth of Auditory Nerve Fibers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7547283

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7547283

Other Identifiers

ISSN

0893-7648,1559-1182

E-ISSN

1559-1182

DOI

10.1007/s12035-020-02092-0

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