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AT101-Loaded Cubosomes as an Alternative for Improved Glioblastoma Therapy

AT101-Loaded Cubosomes as an Alternative for Improved Glioblastoma Therapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7549312

AT101-Loaded Cubosomes as an Alternative for Improved Glioblastoma Therapy

About this item

Full title

AT101-Loaded Cubosomes as an Alternative for Improved Glioblastoma Therapy

Publisher

New Zealand: Dove

Journal title

International journal of nanomedicine, 2020-01, Vol.15, p.7415-7431

Language

English

Formats

Publication information

Publisher

New Zealand: Dove

More information

Scope and Contents

Contents

AT101, the R-(-)-enantiomer of the cottonseed-derived polyphenol gossypol, is a promising drug in glioblastoma multiforme (GBM) therapy due to its ability to trigger autophagic cell death but also to facilitate apoptosis in tumor cells. It does have some limitations such as poor solubility in water-based media and consequent low bioavailability, wh...

Alternative Titles

Full title

AT101-Loaded Cubosomes as an Alternative for Improved Glioblastoma Therapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7549312

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7549312

Other Identifiers

ISSN

1178-2013,1176-9114

E-ISSN

1178-2013

DOI

10.2147/IJN.S265061

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