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Gamete-level immunogenetic incompatibility in humans–towards deeper understanding of fertilization a...

Gamete-level immunogenetic incompatibility in humans–towards deeper understanding of fertilization a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7553942

Gamete-level immunogenetic incompatibility in humans–towards deeper understanding of fertilization and infertility?

About this item

Full title

Gamete-level immunogenetic incompatibility in humans–towards deeper understanding of fertilization and infertility?

Publisher

England: Springer Nature B.V

Journal title

Heredity, 2020-11, Vol.125 (5), p.281-289

Language

English

Formats

Publication information

Publisher

England: Springer Nature B.V

More information

Scope and Contents

Contents

Human leukocyte antigen (HLA) immune genes play an important role in partner selection, but it has remained unclear if nonrandom pairing with respect to parental HLA genes could occur at the level of the gametes. We tested this possibility by investigating whether the sperm fertilization competence in humans is dependent on HLA genotype combination...

Alternative Titles

Full title

Gamete-level immunogenetic incompatibility in humans–towards deeper understanding of fertilization and infertility?

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7553942

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7553942

Other Identifiers

ISSN

0018-067X

E-ISSN

1365-2540

DOI

10.1038/s41437-020-0350-8

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