Baseline IFN-γ and IL-10 expression in PBMCs could predict response to PD-1 checkpoint inhibitors in...
Baseline IFN-γ and IL-10 expression in PBMCs could predict response to PD-1 checkpoint inhibitors in advanced melanoma patients
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Author / Creator
Giunta, Emilio Francesco , Barra, Giusi , De Falco, Vincenzo , Argenziano, Giuseppe , Napolitano, Stefania , Vitale, Pasquale , Zanaletti, Nicoletta , Terminiello, Marinella , Martinelli, Erika , Morgillo, Floriana , Ciardiello, Davide , De Palma, Raffaele , Ciardiello, Fortunato and Troiani, Teresa
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Anti-PD-1 antibodies revolutionized the treatment of advanced melanoma patients. However, one out of three do not respond to this therapy, with an overall poor prognosis. Identification of predictive biomarkers in patients receiving immune-based therapies is necessary for minimizing risk of toxicity and optimizing patient benefit and is still an im...
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Full title
Baseline IFN-γ and IL-10 expression in PBMCs could predict response to PD-1 checkpoint inhibitors in advanced melanoma patients
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7573589
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7573589
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-72711-2