A substrate-trapping strategy to find E3 ubiquitin ligase substrates identifies Parkin and TRIM28 ta...
A substrate-trapping strategy to find E3 ubiquitin ligase substrates identifies Parkin and TRIM28 targets
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The identification of true substrates of an E3 ligase is biologically important but biochemically difficult. In recent years, several techniques for identifying substrates have been developed, but these approaches cannot exclude indirect ubiquitination or have other limitations. Here we develop an E3 ligase substrate-trapping strategy by fusing a t...
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A substrate-trapping strategy to find E3 ubiquitin ligase substrates identifies Parkin and TRIM28 targets
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7576197
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7576197
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-020-01328-y