The AKR1C3/AR‐V7 complex maintains CRPC tumour growth by repressing B4GALT1 expression
The AKR1C3/AR‐V7 complex maintains CRPC tumour growth by repressing B4GALT1 expression
About this item
Full title
Author / Creator
Wang, Bin , Wu, Shiqi , Fang, Yong , Sun, Guangxi , He, Dalin , Hsieh, Jer‐Tsong , Wang, Xinyang , Zeng, Hao and Wu, Kaijie
Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
Formats
Publication information
Publisher
England: John Wiley & Sons, Inc
Subjects
More information
Scope and Contents
Contents
Multiple mechanisms contribute to the survival and growth of metastatic castration‐resistant prostate cancer (mCRPC) cells without androgen, including androgen receptor splice variants (AR‐V) and de novo intratumoral androgen synthesis. AKR1C3 is a critical androgenic enzyme that plays different roles in mCRPC, such as an EMT driver or AR coactivat...
Alternative Titles
Full title
The AKR1C3/AR‐V7 complex maintains CRPC tumour growth by repressing B4GALT1 expression
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7579719
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7579719
Other Identifiers
ISSN
1582-1838
E-ISSN
1582-4934
DOI
10.1111/jcmm.15831
