Direct signaling of TL1A-DR3 on fibroblasts induces intestinal fibrosis in vivo
Direct signaling of TL1A-DR3 on fibroblasts induces intestinal fibrosis in vivo
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Tumor necrosis factor-like cytokine 1A (TL1A,
TNFSF15
) is implicated in inflammatory bowel disease, modulating the location and severity of inflammation and fibrosis. TL1A expression is increased in inflamed mucosa and associated with fibrostenosing Crohn’s disease. Tl1a-overexpression in mice causes spontaneous ileitis, and exacerbates indu...
Alternative Titles
Full title
Direct signaling of TL1A-DR3 on fibroblasts induces intestinal fibrosis in vivo
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7584589
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7584589
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-75168-5
