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Toward Drug-Like Multispecific Antibodies by Design

Toward Drug-Like Multispecific Antibodies by Design

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7589779

Toward Drug-Like Multispecific Antibodies by Design

About this item

Full title

Toward Drug-Like Multispecific Antibodies by Design

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2020-10, Vol.21 (20), p.7496

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

The success of antibody therapeutics is strongly influenced by their multifunctional nature that couples antigen recognition mediated by their variable regions with effector functions and half-life extension mediated by a subset of their constant regions. Nevertheless, the monospecific IgG format is not optimal for many therapeutic applications, an...

Alternative Titles

Full title

Toward Drug-Like Multispecific Antibodies by Design

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7589779

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7589779

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms21207496

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