Rare Germline Genetic Variants and the Risks of Epithelial Ovarian Cancer
Rare Germline Genetic Variants and the Risks of Epithelial Ovarian Cancer
About this item
Full title
Author / Creator
Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publication information
Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
A family history of ovarian or breast cancer is the strongest risk factor for epithelial ovarian cancer (EOC). Germline deleterious variants in the
and
genes confer EOC risks by age 80, of 44% and 17% respectively. The mismatch repair genes, particularly
and
, are also EOC susceptibility genes. Several other DNA repair genes,
,
,<...
Alternative Titles
Full title
Rare Germline Genetic Variants and the Risks of Epithelial Ovarian Cancer
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7589980
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7589980
Other Identifiers
ISSN
2072-6694
E-ISSN
2072-6694
DOI
10.3390/cancers12103046
