Therapeutic effect of a histone demethylase inhibitor in Parkinson’s disease
Therapeutic effect of a histone demethylase inhibitor in Parkinson’s disease
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Iron accumulation in the substantia nigra is recognized as a hallmark of Parkinson’s disease (PD). Therefore, reducing accumulated iron and associated oxidative stress is considered a promising therapeutic strategy for PD. However, current iron chelators have poor membrane permeability and lack cell-type specificity. Here we identified GSK-J4, a hi...
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Full title
Therapeutic effect of a histone demethylase inhibitor in Parkinson’s disease
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7595123
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7595123
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-020-03105-5
