Oxidation of ethidium-based probes by biological radicals: mechanism, kinetics and implications for...
Oxidation of ethidium-based probes by biological radicals: mechanism, kinetics and implications for the detection of superoxide
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Hydroethidine (HE) and hydropropidine (
HPr
+
) are fluorogenic probes used for the detection of the intra- and extracellular superoxide radical anion (
O
2
∙
-
). In this study, we provide evidence that HE and
HPr
+
react rapidly with the biologically relevant radicals, including the hydroxyl radical, peroxyl radic...
Alternative Titles
Full title
Oxidation of ethidium-based probes by biological radicals: mechanism, kinetics and implications for the detection of superoxide
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7596101
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7596101
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-75373-2
