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Hypoxia-inducible factor signaling in pulmonary hypertension

Hypoxia-inducible factor signaling in pulmonary hypertension

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7598042

Hypoxia-inducible factor signaling in pulmonary hypertension

About this item

Full title

Hypoxia-inducible factor signaling in pulmonary hypertension

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2020-11, Vol.130 (11), p.5638-5651

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Pulmonary hypertension (PH) is characterized by pulmonary artery remodeling that can subsequently culminate in right heart failure and premature death. Emerging evidence suggests that hypoxia-inducible factor (HIF) signaling plays a fundamental and pivotal role in the pathogenesis of PH. This Review summarizes the regulation of HIF isoforms and the...

Alternative Titles

Full title

Hypoxia-inducible factor signaling in pulmonary hypertension

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7598042

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7598042

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI137558

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