Hypoxia-inducible factor signaling in pulmonary hypertension
Hypoxia-inducible factor signaling in pulmonary hypertension
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Publisher
United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
Pulmonary hypertension (PH) is characterized by pulmonary artery remodeling that can subsequently culminate in right heart failure and premature death. Emerging evidence suggests that hypoxia-inducible factor (HIF) signaling plays a fundamental and pivotal role in the pathogenesis of PH. This Review summarizes the regulation of HIF isoforms and the...
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Full title
Hypoxia-inducible factor signaling in pulmonary hypertension
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7598042
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7598042
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI137558