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Preventing neuronal edema increases network excitability after traumatic brain injury

Preventing neuronal edema increases network excitability after traumatic brain injury

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7598047

Preventing neuronal edema increases network excitability after traumatic brain injury

About this item

Full title

Preventing neuronal edema increases network excitability after traumatic brain injury

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2020-11, Vol.130 (11), p.6005-6020

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Edema is an important target for clinical intervention after traumatic brain injury (TBI). We used in vivo cellular resolution imaging and electrophysiological recording to examine the ionic mechanisms underlying neuronal edema and their effects on neuronal and network excitability after controlled cortical impact (CCI) in mice. Unexpectedly, we fo...

Alternative Titles

Full title

Preventing neuronal edema increases network excitability after traumatic brain injury

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7598047

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7598047

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI134793

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