Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217
Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217
About this item
Full title
Author / Creator
Northey, Jason J. , Barrett, Alexander S. , Acerbi, Irene , Hayward, Mary-Kate , Talamantes, Stephanie , Dean, Ivory S. , Mouw, Janna K. , Ponik, Suzanne M. , Lakins, Jonathon N. , Huang, Po-Jui , Wu, Junmin , Shi, Quanming , Samson, Susan , Keely, Patricia J. , Mukhtar, Rita A. , Liphardt, Jan T. , Shepherd, John A. , Hwang, E. Shelley , Chen, Yunn-Yi , Hansen, Kirk C. , Littlepage, Laurie E. and Weaver, Valerie M.
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Women with dense breasts have an increased lifetime risk of malignancy that has been attributed to a higher epithelial density. Quantitative proteomics, collagen analysis, and mechanical measurements in normal tissue revealed that stroma in the high-density breast contains more oriented, fibrillar collagen that is stiffer and correlates with higher...
Alternative Titles
Full title
Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217
Authors, Artists and Contributors
Author / Creator
Barrett, Alexander S.
Acerbi, Irene
Hayward, Mary-Kate
Talamantes, Stephanie
Dean, Ivory S.
Mouw, Janna K.
Ponik, Suzanne M.
Lakins, Jonathon N.
Huang, Po-Jui
Wu, Junmin
Shi, Quanming
Samson, Susan
Keely, Patricia J.
Mukhtar, Rita A.
Liphardt, Jan T.
Shepherd, John A.
Hwang, E. Shelley
Chen, Yunn-Yi
Hansen, Kirk C.
Littlepage, Laurie E.
Weaver, Valerie M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7598051
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7598051
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI129249
