The rapamycin analog Everolimus reversibly impairs male germ cell differentiation and fertility in t...
The rapamycin analog Everolimus reversibly impairs male germ cell differentiation and fertility in the mouse
About this item
Full title
Author / Creator
Publisher
United States: Society for the Study of Reproduction
Journal title
Language
English
Formats
Publication information
Publisher
United States: Society for the Study of Reproduction
Subjects
More information
Scope and Contents
Contents
Sirolimus, also known as rapamycin, and its closely related rapamycin analog (rapalog) Everolimus inhibit “mammalian target of rapamycin complex 1” (mTORC1), whose activity is required for spermatogenesis. Everolimus is Food and Drug Administration approved for treating human patients to slow growth of aggressive cancers and preventing organ transp...
Alternative Titles
Full title
The rapamycin analog Everolimus reversibly impairs male germ cell differentiation and fertility in the mouse
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7609841
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7609841
Other Identifiers
ISSN
0006-3363
E-ISSN
1529-7268
DOI
10.1093/biolre/ioaa130
