Distinct metabolic programs established in the thymus control effector functions of γδ T cell subset...
Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments
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Author / Creator
Lopes, Noel , McIntyre, Claire , Martin, Stefania , Raverdeau, Mathilde , Sumaria, Nital , Kohlgruber, Ayano C. , Fiala, Gina , Agudelo, Leandro Z. , Dyck, Lydia , Kane, Harry , Douglas, Aaron , Cunningham, Stephen , Prendeville, Hannah , Loftus, Roisin , Carmody, Colleen , Pierre, Philippe , Kellis, Manolis , Brenner, Michael , Argüello, Rafael J. , Silva-Santos, Bruno , Pennington, Daniel J. and Lynch, Lydia
Publisher
New York: Springer Nature
Journal title
Language
English
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Publisher
New York: Springer Nature
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© The Author(s), under exclusive licence to Springer Nature America, Inc. 2021
Metabolic programming controls immune cell lineages and functions, but little is known about γδ T cell metabolism. Here, we found that γδ T cell subsets making either interferon-γ (IFN-γ) or interleukin (IL)-17 have intrinsically distinct metabolic requirements. Where...
Alternative Titles
Full title
Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments
Authors, Artists and Contributors
Author / Creator
McIntyre, Claire
Martin, Stefania
Raverdeau, Mathilde
Sumaria, Nital
Kohlgruber, Ayano C.
Fiala, Gina
Agudelo, Leandro Z.
Dyck, Lydia
Kane, Harry
Douglas, Aaron
Cunningham, Stephen
Prendeville, Hannah
Loftus, Roisin
Carmody, Colleen
Pierre, Philippe
Kellis, Manolis
Brenner, Michael
Argüello, Rafael J.
Silva-Santos, Bruno
Pennington, Daniel J.
Lynch, Lydia
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7610600
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7610600
Other Identifiers
ISSN
1529-2908,1529-2916
E-ISSN
1529-2916
DOI
10.1038/s41590-020-00848-3
