Population-scale single-cell RNA-seq profiling across dopaminergic neuron differentiation
Population-scale single-cell RNA-seq profiling across dopaminergic neuron differentiation
About this item
Full title
Author / Creator
HipSci Consortium , Jerber, Julie , Seaton, Daniel D. , Cuomo, Anna S. E. , Kumasaka, Natsuhiko , Haldane, James , Steer, Juliette , Patel, Minal , Pearce, Daniel , Andersson, Malin , Bonder, Marc Jan , Mountjoy, Ed , Ghoussaini, Maya , Lancaster, Madeline A. , Marioni, John C. , Merkle, Florian T. , Gaffney, Daniel J. and Stegle, Oliver
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Studying the function of common genetic variants in primary human tissues and during development is challenging. To address this, we use an efficient multiplexing strategy to differentiate 215 human induced pluripotent stem cell (iPSC) lines toward a midbrain neural fate, including dopaminergic neurons, and use single-cell RNA sequencing (scRNA-seq...
Alternative Titles
Full title
Population-scale single-cell RNA-seq profiling across dopaminergic neuron differentiation
Authors, Artists and Contributors
Author / Creator
Jerber, Julie
Seaton, Daniel D.
Cuomo, Anna S. E.
Kumasaka, Natsuhiko
Haldane, James
Steer, Juliette
Patel, Minal
Pearce, Daniel
Andersson, Malin
Bonder, Marc Jan
Mountjoy, Ed
Ghoussaini, Maya
Lancaster, Madeline A.
Marioni, John C.
Merkle, Florian T.
Gaffney, Daniel J.
Stegle, Oliver
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7610897
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7610897
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/s41588-021-00801-6
