Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability
Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability
About this item
Full title
Author / Creator
Geijer, Marit E. , Zhou, Di , Selvam, Kathiresan , Steurer, Barbara , Mukherjee, Chirantani , Evers, Bastiaan , Cugusi, Simona , van Toorn, Marvin , van der Woude, Melanie , Janssens, Roel C. , Kok, Yannick P. , Gong, Wenzhi , Raams, Anja , Lo, Calvin S. Y. , Lebbink, Joyce H. G. , Geverts, Bart , Plummer, Dalton A. , Bezstarosti, Karel , Theil, Arjan F. , Mitter, Richard , Houtsmuller, Adriaan B. , Vermeulen, Wim , Demmers, Jeroen A. A. , Li, Shisheng , van Vugt, Marcel A. T. M. , Lans, Hannes , Bernards, René , Svejstrup, Jesper Q. , Ray Chaudhuri, Arnab , Wyrick, John J. and Marteijn, Jurgen A.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Correct transcription is crucial for life. However, DNA damage severely impedes elongating RNA polymerase II, causing transcription inhibition and transcription-replication conflicts. Cells are equipped with intricate mechanisms to counteract the severe consequence of these transcription-blocking lesions. However, the exact mechanism and factors in...
Alternative Titles
Full title
Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability
Authors, Artists and Contributors
Author / Creator
Zhou, Di
Selvam, Kathiresan
Steurer, Barbara
Mukherjee, Chirantani
Evers, Bastiaan
Cugusi, Simona
van Toorn, Marvin
van der Woude, Melanie
Janssens, Roel C.
Kok, Yannick P.
Gong, Wenzhi
Raams, Anja
Lo, Calvin S. Y.
Lebbink, Joyce H. G.
Geverts, Bart
Plummer, Dalton A.
Bezstarosti, Karel
Theil, Arjan F.
Mitter, Richard
Houtsmuller, Adriaan B.
Vermeulen, Wim
Demmers, Jeroen A. A.
Li, Shisheng
van Vugt, Marcel A. T. M.
Lans, Hannes
Bernards, René
Svejstrup, Jesper Q.
Ray Chaudhuri, Arnab
Wyrick, John J.
Marteijn, Jurgen A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7611218
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7611218
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/s41556-021-00692-z
