Pervasive chromosomal instability and karyotype order in tumour evolution
Pervasive chromosomal instability and karyotype order in tumour evolution
About this item
Full title
Author / Creator
Watkins, Thomas B. K. , Lim, Emilia L. , Petkovic, Marina , Elizalde, Sergi , Birkbak, Nicolai J. , Wilson, Gareth A. , Moore, David A. , Grönroos, Eva , Rowan, Andrew , Dewhurst, Sally M. , Demeulemeester, Jonas , Dentro, Stefan C. , Horswell, Stuart , Au, Lewis , Haase, Kerstin , Escudero, Mickael , Rosenthal, Rachel , Bakir, Maise Al , Xu, Hang , Litchfield, Kevin , Lu, Wei Ting , Mourikis, Thanos P. , Dietzen, Michelle , Spain, Lavinia , Cresswell, George D. , Biswas, Dhruva , Lamy, Philippe , Nordentoft, Iver , Harbst, Katja , Castro-Giner, Francesc , Yates, Lucy R. , Caramia, Franco , Jaulin, Fanny , Vicier, Cécile , Tomlinson, Ian P. M. , Brastianos, Priscilla K. , Cho, Raymond J. , Bastian, Boris C. , Dyrskjøt, Lars , Jönsson, Göran B. , Savas, Peter , Loi, Sherene , Campbell, Peter J. , Andre, Fabrice , Luscombe, Nicholas M. , Steeghs, Neeltje , Tjan-Heijnen, Vivianne C. G. , Szallasi, Zoltan , Turajlic, Samra , Jamal-Hanjani, Mariam , Van Loo, Peter , Bakhoum, Samuel F. , Schwarz, Roland F. , McGranahan, Nicholas and Swanton, Charles
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Chromosomal instability in cancer consists of dynamic changes to the number and structure of chromosomes
1
,
2
. The resulting diversity in somatic copy number alterations (SCNAs) may provide the variation necessary for tumour evolution
1
,
3
,
4
. Here we use multi-sample phasing and SCNA analysis of 1,421 samples fro...
Alternative Titles
Full title
Pervasive chromosomal instability and karyotype order in tumour evolution
Authors, Artists and Contributors
Author / Creator
Lim, Emilia L.
Petkovic, Marina
Elizalde, Sergi
Birkbak, Nicolai J.
Wilson, Gareth A.
Moore, David A.
Grönroos, Eva
Rowan, Andrew
Dewhurst, Sally M.
Demeulemeester, Jonas
Dentro, Stefan C.
Horswell, Stuart
Au, Lewis
Haase, Kerstin
Escudero, Mickael
Rosenthal, Rachel
Bakir, Maise Al
Xu, Hang
Litchfield, Kevin
Lu, Wei Ting
Mourikis, Thanos P.
Dietzen, Michelle
Spain, Lavinia
Cresswell, George D.
Biswas, Dhruva
Lamy, Philippe
Nordentoft, Iver
Harbst, Katja
Castro-Giner, Francesc
Yates, Lucy R.
Caramia, Franco
Jaulin, Fanny
Vicier, Cécile
Tomlinson, Ian P. M.
Brastianos, Priscilla K.
Cho, Raymond J.
Bastian, Boris C.
Dyrskjøt, Lars
Jönsson, Göran B.
Savas, Peter
Loi, Sherene
Campbell, Peter J.
Andre, Fabrice
Luscombe, Nicholas M.
Steeghs, Neeltje
Tjan-Heijnen, Vivianne C. G.
Szallasi, Zoltan
Turajlic, Samra
Jamal-Hanjani, Mariam
Van Loo, Peter
Bakhoum, Samuel F.
Schwarz, Roland F.
McGranahan, Nicholas
Swanton, Charles
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7611706
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7611706
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-020-2698-6
